Giving Compass' Take:

• Researchers report on a new test that can detect opioids in a person’s breath which could be useful in caring for chronic pain patients as well as for checking for illegal drug use.

• How can nonprofits and philanthropists take action against the opioid crisis? What are some other ways to address this epidemic and reduce the number of deaths caused by opioid abuse? 

• Here's how opioids affect the lives of older people. 

“There are a few ways we think this could impact society,” says Cristina Davis, chair of the mechanical and aerospace engineering department at the University of California, Davis, who led the research along with Michael Schivo from the university’s Medical Center.

Doctors and nurses treating chronic pain may need to monitor patients to make sure they are taking their drugs correctly, that their prescribed drugs are being metabolized properly, and that they are not taking additional medications. Blood tests are the gold standard: a reliable, noninvasive test would be a useful alternative.

For the test postdoctoral researcher Eva Borras, Davis, and colleagues developed, subjects breathe normally into a specialized collection device. The device holds condensed droplets from breath for storage in a freezer until testing. Davis’ lab uses mass spectrometry to identify compounds in the samples.

The researchers tested the technique in a small group of patients receiving infusions of pain medications including morphine and hydromorphone, or oral doses of oxycodone. They were therefore able to compare opioid metabolites in breath with both blood samples and the doses given to patients.

Read the full article on testing opioids on the breath by Andy Fell at Futurity.